BDBM142088 US11096924, DASH-inhibitors 2243::US11559537, Compound 2243::US8933056, Ala-boroPro Thioxamide
SMILES C[C@H](N)C(=S)N1CCC[C@H]1B(O)O
InChI Key InChIKey=ZEMFLZQUUHJMGT-WDSKDSINSA-N
Data 16 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 142088
Affinity DataIC50: 0.350nMpH: 2.0Assay Description:The inhibitor solution is prepared by dissolving 3-5 mg of inhibitor in pH 2 solution (0.01 N HCl), such that the concentration of the solution is eq...More data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:EnzymesRecombinant human DPPIV (R&D Systems, Cat. No. 1180-SE)Recombinant human DPP8 (Enzo Life Sciences, Cat. No. BML-SE527)Recombinant human DPP9 (...More data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMAssay Description:This assay is described in Bachovchin et al. Nature Chemical Biology 10, 656-663 (2014). Briefly, purified enzymes are coupled to Luminex microsphere...More data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+4nMpH: 8.0Assay Description:The inhibitor solution is prepared by dissolving 3-5 mg of inhibitor in pH 2 solution (0.01 N HCl), such that the concentration of the solution is eq...More data for this Ligand-Target Pair